Interrogating NCBI PubMed E-Utils API...
Articles from PubMed
Recent Literature Queries
Stored locally in your browserNo search history yet.
Chanakya Review Engine
Progressive expansion (up to ~6,000 words)
Use Google Gemini (2.5 / 3.8 Flash) in Settings for 1M TPM free quota without per-minute token cutoffs.
Selected Articles
0 papersProgressive Drafting in Progress...
Drafting Section 1 of 4...
Chanakya Comprehensive Review Manuscript
Literature Review Studio Ready
Select at least 2 publications in the sidebar, choose your desired length (up to 4,500–6,000 words), and click "Generate Review" to begin progressive drafting.
Custom Metadata Upload & Citation Synthesis
Manually enter unpublished papers, preprints, or external datasets into your session
Batch CSV / JSON Metadata Upload
Upload a structured CSV file with headers:
title, authors, journal, year, doi, abstract
External Citation List Import
Import citations exported from Google Scholar, Europe PMC, Web of Science, or Reference Managers
LLM Provider & API Key Configuration (BYOK)
Your keys remain strictly in your browser's local storage and are never stored on a server
Supports Groq Cloud, Google AI Studio, OpenAI, Anthropic, or OpenRouter keys.
Choose whether your API key persists on this device or lives exclusively in ephemeral browser RAM.
Toggle whether the interactive Chanakya co-pilot pill appears in the bottom right corner
Page 1: PubMed Search & Biological Filtration
Querying NCBI PubMed, filtering MeSH terms, and article selection
1 Smart Keyword Query
Search by genes (TP53, GATA3), pathways, or disease phenotypes. Combine
terms like DNA Methylation, Epigenetics, Glioblastoma.
2 Multi-Parameter Filters
Click the Filters card to specify Organisms (Human, Mouse, Yeast, or custom MeSH), Article Types (Reviews, Clinical Trials), and custom Date Ranges.
3 Selection & Citations
Check the boxes on papers to add them to your synthesis bucket. Use Select Page to add 10 papers instantly, or export individual citations in BibTeX/RIS format.
Page 2: Review Studio & Multi-Paper Synthesis
Generating structured reviews up to 6,000+ words across 4 expansion stages
1 Review Length Profiles
- • Full-Length Review (~6k words): 4 progressive stages with comparative matrix tables.
- • Extended Synthesis (~2.5k words): 1-shot in-depth comparative review.
- • Executive Brief (~1k words): High-level biological executive summary.
2 4-Stage Progressive Pipeline
Stage 1 (0-25%): Executive Landscape & Matrix.
Stage 2 (25-50%): Mechanistic & Epigenetic Networks.
Stage 3 (50-75%): Cross-Study Consensuses.
Stage 4 (75-100%): Translational Roadmaps & Bibliography.
3 Stage Resilience & Exports
If an API bottleneck occurs at 88%, previous sections remain preserved with an in-situ Resume Stage button. Export completed drafts to Word (.doc), Markdown (.md), or Print / PDF via isolated iframe printing.
Page 3: Custom Article Metadata & Preprints
Incorporating unpublished lab findings, bioRxiv/medRxiv preprints, and non-indexed papers
Direct Manual Entry
Enter Title, Authors, Journal/Source (e.g. bioRxiv or Lab Internal Report), DOI, and Abstract. Custom articles receive a unique identifier and integrate directly alongside PubMed citations.
Direct Single-Paper Interrogation
Click Evaluate with Chanakya on any custom article to receive an immediate biological dissection, experimental critique, and clinical relevance report without needing a PubMed PMID.
Page 4: External Imports (Google Scholar, Europe PMC & Reference Managers)
Importing literature from Zotero, Mendeley, EndNote, RIS, BibTeX, and CSV exports
RIS & BibTeX Files
Drag-and-drop .ris or .bib citation exports from Europe PMC,
Google Scholar, or reference managers. The parser automatically extracts tags
(TI, AU, AB, DO).
CSV Spreadsheet Import
Import CSV spreadsheets containing column headers: title,
authors, journal, pubdate, doi, and
abstract.
Raw Text Paste
Paste unformatted citations or lists of titles and abstracts directly into the text box. The regex engine parses them and adds them to your selected articles bucket.
Chanakya Floating Co-Pilot & Single-Paper Analyzer
Interactive conversational co-pilot for genomics and literature interpretation
Conversational Literature Inquiries
Click the floating Chanakya badge in the bottom-right corner to open the co-pilot drawer. You can ask free-form biomedical questions, request experimental designs, or query epigenetic mechanisms across known biomarkers.
Single-Paper Biological Dissection
Click Evaluate with Chanakya on any PubMed search card to open the dedicated analysis modal. It provides:
- • Executive Biological Takeaway: Core scientific discovery.
- • Mechanisms & Pathways: Biochemical cascades and genes.
- • Experimental Rigor & Limitations: Sample size, models, and caveats.
Page 5: Settings, Models & API Quota Strategies
How to configure your API keys and select models based on review length
Google Gemini offers a free tier with 1,000,000 Tokens Per Minute (TPM) and 15 Requests Per Minute (RPM). This allows synthesizing full 6,000-word manuscripts across 10+ papers seamlessly without rate-limit bottlenecks.
gemini-2.5-flash or gemini-3.8-flash
Groq generates responses at 300+ tokens/sec. However, their on-demand tier enforces an 8,000 TPM ceiling. For 4-stage reviews, our engine automatically paces drafts with 50-second cooling intervals to reset tokens safely.
llama-3.3-70b-versatile or
llama-3.1-8b-instant
Supports gpt-4o, gpt-4o-mini, and STEM reasoning models
(o3-mini, o1).
Supports claude-3-7-sonnet and claude-3-5-haiku for deep
academic prose and analytical rigor.
Universal endpoint for DeepSeek R1, Llama 3.3, and multi-model routing under a single API key.